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Family Practice

Joseph A. Destefano Iii, MD

Works at hospitals in Gaffney, SC · Spartanburg, SC · South Carolina

Summary

Dr. Joseph A. Destefano Iii, MD is a family doctor at 1200 E Main St, Suite 12, Spartanburg, SC 29307. Phone: (864) 560-9260. Accepts Medicare assignment. NPI 1275190738. Source: CMS National Downloadable File, updated October 2, 2026; CMS Facility Affiliation Data, updated October 2, 2026.

  • Specialty: Family doctor (Medicare lists Family Practice)
  • Address: 1200 E Main St, Suite 12, Spartanburg, SC 29307 · Directions (4 more locations)
  • Phone: (864) 560‑9260
  • Medicare: Accepts Medicare assignment
  • Hospitals: Cherokee Medical Center, Spartanburg Medical Center
  • Group practice: Spartanburg Medical Center (+1 more)
  • Medical school: University Of South Carolina School Of Medicine · graduated 2019 (7 years since medical school)
  • Gender (as listed): Male

From official Medicare data

This page shows what Medicare's official clinician data says about Joseph A. Destefano Iii, joined by NPI number (data updated October 2, 2026). It is not a recommendation or a rating. Call the office or hospital to confirm before you go.

In a medical emergency, call 911.

Quick answers

Does Joseph A. Destefano Iii accept Medicare assignment?
Yes. Medicare's clinician data says Joseph A. Destefano Iii accepts Medicare assignment (the Medicare-approved amount as full payment for covered services), as of October 2, 2026. Ask the office to confirm before your visit.
What is Joseph A. Destefano Iii's NPI number?
1275190738. The NPI (National Provider Identifier) is the clinician's permanent federal ID; you can look it up in the official NPI Registry.

Hospitals where Joseph A. Destefano Iii works

Medicare's Facility Affiliation Data lists Joseph A. Destefano Iii at these hospitals (updated October 2, 2026). Each hospital page shows its address, phone, emergency services, Medicare rating and all its clinicians. Star rating and emergency services: Hospital General Information (CMS), data updated October 26, 2026.

Practice locations

Addresses where Joseph A. Destefano Iii is enrolled with Medicare (CMS data updated October 2, 2026).

Group practices

Medicare enrollment lists Joseph A. Destefano Iii as a member of these groups (CMS data updated October 2, 2026).

  • Spartanburg Medical Center1,078 clinicians in the group
  • Cherokee Medical Center40 clinicians in the group

Specialties

Find other Family Practice doctors in South Carolina →

Other family doctors in Spartanburg

Clinicians with the same Medicare primary specialty in Spartanburg, SC — not a recommendation.

All family doctors in Spartanburg →

Other clinicians in Spartanburg Medical Center

Medicare enrollment lists these clinicians in the same group practice — not a recommendation.

Clinician information

CredentialMD
Medical schoolUniversity Of South Carolina School Of Medicine
Graduation year2019 (7 years since medical school)
Gender (as listed)Male
Medicare assignmentAccepts (Medicare-approved amount as full payment)
NPI (National Provider Identifier)1275190738
CorrectionsReport an error or suggest an update →

Most corrections must be made at the source: clinicians update their NPI Registry record (NPPES) and their Medicare enrollment (PECOS); this page follows the next data release.

Sources

  1. Facility Affiliation Data — Centers for Medicare & Medicaid Services (CMS), data updated October 2, 2026, retrieved October 29, 2026
  2. Hospital General Information — CMS, data updated October 26, 2026, retrieved November 13, 2026
  3. National Downloadable File (Doctors and Clinicians) — CMS, data updated October 2, 2026, retrieved October 29, 2026
  4. NPI Registry — U.S. Department of Health and Human Services (NPPES), the clinician’s official record
  5. Medicare Care Compare — official Medicare tool to look up clinicians