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Brand-name prescription medicine

Zestril

Generic name: Lisinopril

FDA application holder: Twi Pharms

Official data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the NDC Directory, Drugs@FDA, the official labels and recall reports; pharmacy costs come from the Centers for Medicare & Medicaid Services (CMS). Each fact shows its source and date.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or switch any medicine, including a switch between a brand and a generic.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

Quick answers

What is Zestril?
Zestril is a brand name of Lisinopril, a prescription medicine. The FDA NDC Directory lists 6 Zestril products in 6 strengths and forms.
Who makes Zestril?
Twi Pharms holds the FDA application for Zestril (NDA019777, approved May 19, 1988).
Is there a generic or store brand of Zestril?
Yes. The FDA NDC Directory lists 261 other products with the same active ingredients, strength and form as a Zestril product, 261 of them generic. Ask your pharmacist whether one is right for you.
What do pharmacies pay for Zestril?
CMS lists a National Average Drug Acquisition Cost (NADAC) for 1 Zestril strength and form (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
Has Zestril been recalled?
No recall linked to Zestril products (by their NDC code or label) appears in the FDA enforcement reports we use.

What Zestril is

Each Zestril product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.

Lisinopril · prescription medicine

Strength and formProduct namesSame medicine, other namesLabel
lisinopril 10 mg
tablet (oral)
Zestril 55 products, 31 companies DailyMed
lisinopril 2.5 mg
tablet (oral)
Zestril 39 products, 24 companies DailyMed
lisinopril 20 mg
tablet (oral)
Zestril 52 products, 31 companies DailyMed
lisinopril 30 mg
tablet (oral)
Zestril 24 products, 20 companies DailyMed
lisinopril 40 mg
tablet (oral)
Zestril 43 products, 28 companies DailyMed
lisinopril 5 mg
tablet (oral)
Zestril 48 products, 29 companies DailyMed

Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Lisinopril →

FDA approval

  • NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
FDA applications of Zestril products (Drugs@FDA)
ApplicationHolderFirst approvedProducts
NDA019777Twi PharmsMay 19, 19886

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Zestril, by strength and form
Strength and formGeneric or brandPharmacies pay
lisinopril 10 mg
tablet
Brand: Zestril $12.52 per tablet
Generic of the same strength and form: $0.0180 per tablet

NADAC list of November 4, 2026; these prices took effect on March 18, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that list Zestril

The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Zestril products.

Recalls

No recall linked to Zestril products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026

Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.

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