Quick answers
- What is Synthroid?
- Synthroid is a brand name of Levothyroxine, a prescription medicine. The FDA NDC Directory lists 12 Synthroid products in 12 strengths and forms.
- Who makes Synthroid?
- Abbvie holds the FDA application for Synthroid (NDA021402, approved July 24, 2002).
- Is there a generic or store brand of Synthroid?
- Yes. The FDA NDC Directory lists 338 other products with the same active ingredients, strength and form as a Synthroid product, 250 of them generic. Ask your pharmacist whether one is right for you.
- What do pharmacies pay for Synthroid?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 12 Synthroid strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Synthroid been recalled?
- FDA enforcement reports list 5 recalls of Synthroid products; the newest started October 17, 2023. A recall usually concerns specific lots, not every product.
What Synthroid is
Each Synthroid product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Levothyroxine · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| levothyroxine sodium 100 ug tablet (oral) | Synthroid | 37 products, 22 companies | DailyMed |
| levothyroxine sodium 112 ug tablet (oral) | Synthroid | 28 products, 16 companies | DailyMed |
| levothyroxine sodium 125 ug tablet (oral) | Synthroid | 31 products, 18 companies | DailyMed |
| levothyroxine sodium 137 ug tablet (oral) | Synthroid | 28 products, 19 companies | DailyMed |
| levothyroxine sodium 150 ug tablet (oral) | Synthroid | 26 products, 17 companies | DailyMed |
| levothyroxine sodium 175 ug tablet (oral) | Synthroid | 25 products, 15 companies | DailyMed |
| levothyroxine sodium 200 ug tablet (oral) | Synthroid | 25 products, 16 companies | DailyMed |
| levothyroxine sodium 25 ug tablet (oral) | Synthroid | 27 products, 17 companies | DailyMed |
| levothyroxine sodium 300 ug tablet (oral) | Synthroid | 9 products, 8 companies | DailyMed |
| levothyroxine sodium 50 ug tablet (oral) | Synthroid | 36 products, 19 companies | DailyMed |
| levothyroxine sodium 75 ug tablet (oral) | Synthroid | 34 products, 21 companies | DailyMed |
| levothyroxine sodium 88 ug tablet (oral) | Synthroid | 32 products, 16 companies | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Levothyroxine →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| NDA021402 | Abbvie | July 24, 2002 | 12 |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| levothyroxine sodium 100 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0495 per tablet |
| levothyroxine sodium 112 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0579 per tablet |
| levothyroxine sodium 125 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0575 per tablet |
| levothyroxine sodium 137 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0633 per tablet |
| levothyroxine sodium 150 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0566 per tablet |
| levothyroxine sodium 175 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0748 per tablet |
| levothyroxine sodium 200 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0849 per tablet |
| levothyroxine sodium 25 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0352 per tablet |
| levothyroxine sodium 300 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.1095 per tablet |
| levothyroxine sodium 50 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0401 per tablet |
| levothyroxine sodium 75 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0468 per tablet |
| levothyroxine sodium 88 ug tablet | Brand: Synthroid | $1.66 per tablet Generic of the same strength and form: $0.0476 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Synthroid
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Synthroid products.
- AbbVie Inc.12 products
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
October 17, 2023 · Class III · Ongoing · D-0088-2024
Labeling: Wrong Barcode- One (1) of every forty (40) unit dose blister will contain incorrect barcode information that causes a 125mcg unit dose is scanned as 200mcg unit dose.
Synthroid, Levothyroxine Sodium Tablets, USP 125mcg (0.125mg), 100-count bottle, Rx Only AbbVie Inc. North Chicago, IL 60064, U.S.A. NDC 0074-7068-11 — AbbVie Inc.
-
December 4, 2012 · Class II · Terminated · D-107-2013
Labeling: Error on Declared Strength. Product labeled to contain 150 mcg tablets actually contained 75 mcg tablets.
Synthroid (Levothyroxine Sodium) tablets, 150 mcg (0.15 mg), 90 tablets per bottle, Rx Only, NDC 0074-7069-90; ABBOTT LABORATORIES NORTH CHICAGO, IL 60064 U.S.A. — Abbott Laboratories
-
July 19, 2012 · Class II · Terminated · D-1695-2012
Defective Container: A number of Synthroid bottles have a localized thin wall defect on the bottom which may potentially impact the stability of the tablets.
Synthroid (levothyroxine sodium) Tablets USP, 75 mcg, Rx Only, 90-Count Bottle, Abbott Laboratories, North Chicago, IL 60064, NDC: 0074-5182-90. — Abbott Laboratories
-
July 19, 2012 · Class II · Terminated · D-1696-2012
Defective Container: A number of Synthroid bottles have a localized thin wall defect on the bottom which may potentially impact the stability of the tablets.
Synthroid (levothyroxine sodium) Tablets USP, 112 mcg, Rx Only, 90-Count Bottle, Abbott Laboratories, North Chicago, IL 60064, NDC: 0074-9296-90 — Abbott Laboratories
-
July 19, 2012 · Class II · Terminated · D-1694-2012
Defective Container: A number of Synthroid bottles have a localized thin wall defect on the bottom which may potentially impact the stability of the tablets.
Synthroid (levothyroxine sodium) Tablets USP, 50 mcg, Rx Only, 90-Count Bottle, Abbott Laboratories, North Chicago, IL 60064, NDC: 0074-4552-90. — Abbott Laboratories
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.