Quick answers
- What is Premarin?
- Premarin is a brand name of Estrogens, conjugated, a prescription medicine. The FDA NDC Directory lists 8 Premarin products in 6 strengths and forms.
- Who makes Premarin?
- Wyeth Pharms holds the FDA application for Premarin (NDA004782, approved May 8, 1942). 1 other company (repackagers or distributors) also list Premarin products.
- Is there a generic or store brand of Premarin?
- Yes. The FDA NDC Directory lists 10 other products with the same active ingredients, strength and form as a Premarin product, 10 of them generic. Ask your pharmacist whether one is right for you.
- What do pharmacies pay for Premarin?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 5 Premarin strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Premarin been recalled?
- FDA enforcement reports list 1 recall of Premarin products; the newest started September 15, 2016. A recall usually concerns specific lots, not every product.
What Premarin is
Each Premarin product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Estrogens, conjugated · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| estrogens, conjugated 0.3 mg tablet, film coated (oral) | Premarin | 2 products, 2 companies | DailyMed |
| estrogens, conjugated 0.45 mg tablet, film coated (oral) | Premarin | 2 products, 2 companies | DailyMed |
| estrogens, conjugated 0.625 mg tablet, film coated (oral) | Premarin | 2 products, 2 companies | DailyMed |
| estrogens, conjugated 0.9 mg tablet, film coated (oral) | Premarin | 2 products, 2 companies | DailyMed |
| estrogens, conjugated 1.25 mg tablet, film coated (oral) | Premarin | 2 products, 2 companies | DailyMed |
| estrogens, conjugated 25 mg/5 mL injection, powder, lyophilized, for solution (intramuscular, intravenous) | Premarin | None listed | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Estrogens, conjugated →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| estrogens, conjugated 0.3 mg tablet, film coated | Brand: Premarin | $6.95 per tablet Generic of the same strength and form: $5.30 per tablet |
| estrogens, conjugated 0.45 mg tablet, film coated | Brand: Premarin | $6.95 per tablet Generic of the same strength and form: $5.35 per tablet |
| estrogens, conjugated 0.625 mg tablet, film coated | Brand: Premarin | $6.94 per tablet Generic of the same strength and form: $5.38 per tablet |
| estrogens, conjugated 0.9 mg tablet, film coated | Brand: Premarin | $6.93 per tablet Generic of the same strength and form: $5.57 per tablet |
| estrogens, conjugated 1.25 mg tablet, film coated | Brand: Premarin | $6.95 per tablet Generic of the same strength and form: $5.47 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Premarin
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Premarin products.
- Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.6 products
- A-S Medication Solutions2 products
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
September 15, 2016 · Class III · Terminated · D-1528-2016
Labeling: Incorrect or Missing Lot and/or Exp Date: Bottles were incorrectly labeled with an expiry date of 11/17; the correct date is 09/17.
PREMARIN (conjugated estrogen tablets, USP) 1.25 mg, 1000- count bottle, Rx only, Distributed by: Wyeth Pharmaceuticals Inc. A subsidiary of Pfizer Inc. Philadelphia, PA 19101, NDC 0046-1104-91 — Pfizer Inc.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.