Quick answers
- What is Marcaine with Epinephrine?
- Marcaine with Epinephrine is a brand name of Bupivacaine hydrochloride and epinephrine bitartrate, a prescription medicine. The FDA NDC Directory lists 11 Marcaine with Epinephrine products in 4 strengths and forms.
- Who makes Marcaine with Epinephrine?
- Hospira holds the FDA application for Marcaine with Epinephrine (NDA016964, approved October 3, 1972). 1 other company (repackagers or distributors) also list Marcaine with Epinephrine products.
- Is there a generic or store brand of Marcaine with Epinephrine?
- Other products of Bupivacaine hydrochloride and epinephrine bitartrate are listed with the FDA, but none in exactly the same strength and form as a Marcaine with Epinephrine product.
- Has Marcaine with Epinephrine been recalled?
- No recall linked to Marcaine with Epinephrine products (by their NDC code or label) appears in the FDA enforcement reports we use.
What Marcaine with Epinephrine is
Each Marcaine with Epinephrine product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Bupivacaine hydrochloride and epinephrine bitartrate · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| bupivacaine hydrochloride 2.5 mg/mL · epinephrine bitartrate 0.0091 mg/mL injection, solution (infiltration, perineural) | Marcaine with Epinephrine | None listed | DailyMed |
| bupivacaine hydrochloride 2.5 mg/mL · epinephrine bitartrate 0.0091 mg/mL injection, solution (epidural, infiltration, intracaudal, perineural) | Marcaine with Epinephrine | None listed | DailyMed |
| bupivacaine hydrochloride 5 mg/mL · epinephrine bitartrate 0.0091 mg/mL injection, solution (perineural) | Marcaine with Epinephrine | None listed | DailyMed |
| bupivacaine hydrochloride 5 mg/mL · epinephrine bitartrate 0.0091 mg/mL injection, solution (epidural, intracaudal, perineural) | Marcaine with Epinephrine | None listed | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Bupivacaine hydrochloride and epinephrine bitartrate →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| NDA016964 | Hospira | October 3, 1972 | 11 |
Companies that list Marcaine with Epinephrine
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Marcaine with Epinephrine products.
- Hospira, Inc.10 products
- Henry Schein, Inc.1 product
Recalls
No recall linked to Marcaine with Epinephrine products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.