Quick answers
- What is Janumet XR?
- Janumet XR is a brand name of Sitagliptin and metformin hydrochloride, a prescription medicine. The FDA NDC Directory lists 4 Janumet XR products in 3 strengths and forms.
- Who makes Janumet XR?
- MSD Sub Merck holds the FDA application for Janumet XR (NDA202270, approved February 2, 2012). 1 other company (repackagers or distributors) also list Janumet XR products.
- Is there a generic or store brand of Janumet XR?
- Yes. The FDA NDC Directory lists 3 other products with the same active ingredients, strength and form as a Janumet XR product, 3 of them generic. Ask your pharmacist whether one is right for you.
- What do pharmacies pay for Janumet XR?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 3 Janumet XR strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Janumet XR been recalled?
- No recall linked to Janumet XR products (by their NDC code or label) appears in the FDA enforcement reports we use.
What Janumet XR is
Each Janumet XR product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Sitagliptin and metformin hydrochloride · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| metformin hydrochloride 1000 mg · sitagliptin phosphate 100 mg tablet, film coated, extended release (oral) | Janumet XR | 1 product, 1 company | DailyMed |
| metformin hydrochloride 1000 mg · sitagliptin phosphate 50 mg tablet, film coated, extended release (oral) | Janumet XR | 1 product, 1 company | DailyMed |
| metformin hydrochloride 500 mg · sitagliptin phosphate 50 mg tablet, film coated, extended release (oral) | Janumet XR | 1 product, 1 company | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Sitagliptin and metformin hydrochloride →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| NDA202270 | MSD Sub Merck | February 2, 2012 | 4 |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| metformin hydrochloride 1000 mg · sitagliptin phosphate 100 mg tablet, film coated, extended release | Brand: Janumet XR | $10.55 per tablet Generic of the same strength and form: $8.34 per tablet |
| metformin hydrochloride 1000 mg · sitagliptin phosphate 50 mg tablet, film coated, extended release | Brand: Janumet XR | $5.28 per tablet Generic of the same strength and form: $4.18 per tablet |
| metformin hydrochloride 500 mg · sitagliptin phosphate 50 mg tablet, film coated, extended release | Brand: Janumet XR | $5.28 per tablet Generic of the same strength and form: $3.74 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Janumet XR
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Janumet XR products.
- Merck Sharp & Dohme LLC3 products
- A-S Medication Solutions1 product
Recalls
No recall linked to Janumet XR products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.