Quick answers
- What is Invokamet XR?
- Invokamet XR is a brand name of Canagliflozin and metformin hydrochloride, a prescription medicine. The FDA NDC Directory lists 4 Invokamet XR products in 4 strengths and forms.
- Who makes Invokamet XR?
- Janssen Pharms holds the FDA application for Invokamet XR (NDA205879, approved September 20, 2016).
- Is there a generic or store brand of Invokamet XR?
- Other products of Canagliflozin and metformin hydrochloride are listed with the FDA, but none in exactly the same strength and form as a Invokamet XR product.
- What do pharmacies pay for Invokamet XR?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 4 Invokamet XR strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Invokamet XR been recalled?
- FDA enforcement reports list 1 recall of Invokamet XR products; the newest started October 19, 2016. A recall usually concerns specific lots, not every product.
What Invokamet XR is
Each Invokamet XR product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Canagliflozin and metformin hydrochloride · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| canagliflozin 150 mg · metformin hydrochloride 1000 mg tablet, film coated, extended release (oral) | Invokamet XR | None listed | DailyMed |
| canagliflozin 150 mg · metformin hydrochloride 500 mg tablet, film coated, extended release (oral) | Invokamet XR | None listed | DailyMed |
| canagliflozin 50 mg · metformin hydrochloride 1000 mg tablet, film coated, extended release (oral) | Invokamet XR | None listed | DailyMed |
| canagliflozin 50 mg · metformin hydrochloride 500 mg tablet, film coated, extended release (oral) | Invokamet XR | None listed | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Canagliflozin and metformin hydrochloride →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| NDA205879 | Janssen Pharms | September 20, 2016 | 4 |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| canagliflozin 150 mg · metformin hydrochloride 1000 mg tablet, film coated, extended release | Brand: Invokamet XR | $9.52 per tablet |
| canagliflozin 150 mg · metformin hydrochloride 500 mg tablet, film coated, extended release | Brand: Invokamet XR | $9.56 per tablet |
| canagliflozin 50 mg · metformin hydrochloride 1000 mg tablet, film coated, extended release | Brand: Invokamet XR | $9.69 per tablet |
| canagliflozin 50 mg · metformin hydrochloride 500 mg tablet, film coated, extended release | Brand: Invokamet XR | $9.68 per tablet |
NADAC list of November 4, 2026; these prices took effect between December 17, 2025 and October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Invokamet XR
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Invokamet XR products.
- Janssen Pharmaceuticals, Inc.4 products
Recalls
From FDA enforcement reports, matched by the product’s NDC code or label. A recall usually covers specific lots: check the lot number on your package and ask your pharmacist. Do not stop a medicine on your own.
-
October 19, 2016 · Class III · Terminated · D-0115-2017
Labeling: Incorrect or Missing Package Insert - Xarelto prescribing information outserts may be affixed to the exterior of Invokamet bottles in place of the Invokamet prescribing information outsert.
Invokamet (canagliflozin and metformin HCl) tablets, 150 mg/1,000 mg, 60-count bottle, Rx only, Finished product manufactured by: Janssen Ortho, LLC, Gurabo PR 00778, Manufactured for: Janssen Pharmaceuticals, Inc., Titu — Janssen Ortho L.L.C.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.