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Brand-name prescription medicine

Effexor XR

Generic name: Venlafaxine hydrochloride

FDA application holder: Upjohn

Official data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the NDC Directory, Drugs@FDA, the official labels and recall reports; pharmacy costs come from the Centers for Medicare & Medicaid Services (CMS). Each fact shows its source and date.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or switch any medicine, including a switch between a brand and a generic.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

Quick answers

What is Effexor XR?
Effexor XR is a brand name of Venlafaxine hydrochloride, a prescription medicine. The FDA NDC Directory lists 3 Effexor XR products in 3 strengths and forms.
Who makes Effexor XR?
Upjohn holds the FDA application for Effexor XR (NDA020699, approved October 20, 1997).
Is there a generic or store brand of Effexor XR?
Yes. The FDA NDC Directory lists 159 other products with the same active ingredients, strength and form as a Effexor XR product, 159 of them generic. Ask your pharmacist whether one is right for you.
What do pharmacies pay for Effexor XR?
CMS lists a National Average Drug Acquisition Cost (NADAC) for 3 Effexor XR strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
Has Effexor XR been recalled?
No recall linked to Effexor XR products (by their NDC code or label) appears in the FDA enforcement reports we use.

What Effexor XR is

Each Effexor XR product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.

Venlafaxine hydrochloride · prescription medicine

Strength and formProduct namesSame medicine, other namesLabel
venlafaxine hydrochloride 150 mg
capsule, extended release (oral)
Effexor XR 50 products, 32 companies DailyMed
venlafaxine hydrochloride 37.5 mg
capsule, extended release (oral)
Effexor XR 49 products, 34 companies DailyMed
venlafaxine hydrochloride 75 mg
capsule, extended release (oral)
Effexor XR 60 products, 37 companies DailyMed

Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Venlafaxine hydrochloride →

FDA approval

  • NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
FDA applications of Effexor XR products (Drugs@FDA)
ApplicationHolderFirst approvedProducts
NDA020699UpjohnOctober 20, 19973

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Effexor XR, by strength and form
Strength and formGeneric or brandPharmacies pay
venlafaxine hydrochloride 150 mg
capsule, extended release
Brand: Effexor XR $21.62 per capsule
Generic of the same strength and form: $0.1225 per capsule
venlafaxine hydrochloride 37.5 mg
capsule, extended release
Brand: Effexor XR $17.72 per capsule
Generic of the same strength and form: $0.0791 per capsule
venlafaxine hydrochloride 75 mg
capsule, extended release
Brand: Effexor XR $19.81 per capsule
Generic of the same strength and form: $0.0801 per capsule

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that list Effexor XR

The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Effexor XR products.

Recalls

No recall linked to Effexor XR products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026

Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.

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