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Brand-name prescription medicine

Depo-Provera

Generic name: Medroxyprogesterone acetate

FDA application holder: Pfizer

Official data, not advice

Everything here comes from the U.S. Food and Drug Administration (FDA): the NDC Directory, Drugs@FDA, the official labels and recall reports; pharmacy costs come from the Centers for Medicare & Medicaid Services (CMS). Each fact shows its source and date.

This page is not medical advice. Talk to your doctor or pharmacist before you start, stop or switch any medicine, including a switch between a brand and a generic.

In an emergency, call 911. If someone may have taken too much of a medicine, call Poison Help: 1‑800‑222‑1222.

Quick answers

What is Depo-Provera?
Depo-Provera is a brand name of Medroxyprogesterone acetate, a prescription medicine. The FDA NDC Directory lists 2 Depo-Provera products in 1 strength and form.
Who makes Depo-Provera?
Pfizer holds the FDA application for Depo-Provera (NDA020246, approved October 29, 1992).
Is there a generic or store brand of Depo-Provera?
Yes. The FDA NDC Directory lists 15 other products with the same active ingredients, strength and form as a Depo-Provera product, 15 of them generic. Ask your pharmacist whether one is right for you.
What do pharmacies pay for Depo-Provera?
CMS lists a National Average Drug Acquisition Cost (NADAC) for 1 Depo-Provera strength and form (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
Has Depo-Provera been recalled?
No recall linked to Depo-Provera products (by their NDC code or label) appears in the FDA enforcement reports we use.

What Depo-Provera is

Each Depo-Provera product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.

Medroxyprogesterone acetate · prescription medicine

Strength and formProduct namesSame medicine, other namesLabel
medroxyprogesterone acetate 150 mg/mL
injection, suspension (intramuscular)
Depo-Provera 15 products, 10 companies DailyMed

Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Medroxyprogesterone acetate →

FDA approval

  • NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
FDA applications of Depo-Provera products (Drugs@FDA)
ApplicationHolderFirst approvedProducts
NDA020246PfizerOctober 29, 19922

What pharmacies pay (NADAC)

The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.

This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.

NADAC per unit for Depo-Provera, by strength and form
Strength and formGeneric or brandPharmacies pay
medroxyprogesterone acetate 150 mg/mL
injection, suspension
Brand: Depo-Provera $50.12–$52.26 per mL
2 packages, lowest to highest
Generic of the same strength and form: $17.86–$26.90 per mL

NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.

Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →

Companies that list Depo-Provera

The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Depo-Provera products.

Recalls

No recall linked to Depo-Provera products (by their NDC code or label) appears in the FDA enforcement reports.

Sources

  1. NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  2. Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  3. Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
  4. Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
  5. NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026

Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.

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