Quick answers
- What is Depakote?
- Depakote is a brand name of Divalproex sodium, a prescription medicine. The FDA NDC Directory lists 3 Depakote products in 3 strengths and forms.
- Who makes Depakote?
- Abbvie holds the FDA application for Depakote (NDA018723, approved March 10, 1983).
- Is there a generic or store brand of Depakote?
- Yes. The FDA NDC Directory lists 89 other products with the same active ingredients, strength and form as a Depakote product, 89 of them generic. Ask your pharmacist whether one is right for you.
- What do pharmacies pay for Depakote?
- CMS lists a National Average Drug Acquisition Cost (NADAC) for 3 Depakote strengths and forms (see the table below). That is what pharmacies pay to buy it, not what you pay: your price depends on your insurance and your pharmacy.
- Has Depakote been recalled?
- No recall linked to Depakote products (by their NDC code or label) appears in the FDA enforcement reports we use.
What Depakote is
Each Depakote product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Divalproex sodium · prescription medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| divalproex sodium 125 mg tablet, delayed release (oral) | Depakote | 15 products, 13 companies | DailyMed |
| divalproex sodium 250 mg tablet, delayed release (oral) | Depakote | 40 products, 27 companies | DailyMed |
| divalproex sodium 500 mg tablet, delayed release (oral) | Depakote | 34 products, 22 companies | DailyMed |
Its page lists every product and company, the FDA label’s uses and boxed warning, approvals, shortages and recalls: Divalproex sodium →
FDA approval
- NDA: New Drug Application: how a new (usually brand-name) medicine is approved.
| Application | Holder | First approved | Products |
|---|---|---|---|
| NDA018723 | Abbvie | March 10, 1983 | 3 |
What pharmacies pay (NADAC)
The National Average Drug Acquisition Cost (NADAC) is the average price U.S. retail pharmacies paid to buy one unit of a medicine (one tablet, one mL or one gram), from a monthly survey of pharmacy invoices by the Centers for Medicare & Medicaid Services (CMS). State Medicaid programs use it to pay pharmacies.
This is not the price you pay. What you pay depends on your insurance (copay or coinsurance), your pharmacy and any discounts, and pharmacies also charge for filling a prescription. Ask your pharmacist or your health plan what your price will be.
| Strength and form | Generic or brand | Pharmacies pay |
|---|---|---|
| divalproex sodium 125 mg tablet, delayed release | Brand: Depakote | $2.06 per tablet Generic of the same strength and form: $0.0532 per tablet |
| divalproex sodium 250 mg tablet, delayed release | Brand: Depakote | $4.04 per tablet Generic of the same strength and form: $0.0847 per tablet |
| divalproex sodium 500 mg tablet, delayed release | Brand: Depakote | $7.46 per tablet Generic of the same strength and form: $0.1561 per tablet |
NADAC list of November 4, 2026; these prices took effect on October 21, 2026. Shown only where a package’s NDC code matches the NADAC list exactly, and only for that exact strength and form: nothing is averaged across strengths. Strengths and forms not listed here have no NADAC price.
Source: NADAC (National Average Drug Acquisition Cost) 2026, data.medicaid.gov (CMS) →
Companies that list Depakote
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Depakote products.
- AbbVie Inc.3 products
Recalls
No recall linked to Depakote products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.