Quick answers
- What is Afrin?
- Afrin is a brand name of Oxymetazoline, an over-the-counter medicine. The FDA NDC Directory lists 13 Afrin products in 6 strengths and forms.
- Who makes Afrin?
- Bayer HealthCare LLC. lists 9 of the 13 Afrin products in the FDA NDC Directory.
- Is there a generic or store brand of Afrin?
- Yes. The FDA NDC Directory lists 256 other products with the same active ingredients, strength and form as a Afrin product, 256 of them generic or store brands. Ask your pharmacist whether one is right for you.
- Has Afrin been recalled?
- No recall linked to Afrin products (by their NDC code or label) appears in the FDA enforcement reports we use.
What Afrin is
Each Afrin product as listed in the FDA NDC Directory, by active ingredient, strength and form, with its official label. “Same medicine, other names” counts the other products with exactly the same active ingredients, strength and form (generic versions, store brands and other brands); inactive ingredients can differ.
Oxymetazoline · over-the-counter medicine
| Strength and form | Product names | Same medicine, other names | Label |
|---|---|---|---|
| oxymetazoline hydrochloride 0.05 mg/mL spray, metered (nasal) | Afrin No-Drip Allergy Sinus | None listed | DailyMed |
| oxymetazoline hydrochloride 0.05% spray (nasal) | Afrin Original, Afrin Severe Congestion | 110 products, 50 companies | DailyMed |
| oxymetazoline hydrochloride 0.05% spray (topical) | Afrin | 110 products, 50 companies | DailyMed |
| oxymetazoline hydrochloride 0.05% spray, metered (nasal) | Afrin No Drip Original Pump Mist, Afrin No Drip Severe Congestion, Afrin No Drip Extra Moisturizing, Afrin Original Pump Mist | 20 products, 15 companies | DailyMed |
| oxymetazoline hydrochloride 0.5 mg/mL spray (nasal) | Afrin NoDrip Allergy Sinus Night, Afrin Original Nasal | 16 products, 11 companies | DailyMed |
| oxymetazoline hydrochloride 0.5% spray (nasal) | Afrin Allergy Sinus Nasal | None listed | DailyMed |
Its page quotes the Drug Facts label and lists every brand and store brand: Oxymetazoline →
FDA approval
Afrin products are sold under an FDA over-the-counter monograph: rules that set the allowed active ingredients, strengths and label wording, so these products do not need an individual FDA approval.
Companies that list Afrin
The company named on the package (holder, repackager or distributor), as listed in the FDA NDC Directory, with its number of Afrin products.
- Bayer HealthCare LLC.9 products
- Lil' Drug Store Products, Inc.2 products
- Navajo Manufacturing Company Inc.1 product
- JC World Bell Wholesale Co., Inc.1 product
Recalls
No recall linked to Afrin products (by their NDC code or label) appears in the FDA enforcement reports.
Sources
- NDC Directory (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drugs@FDA (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug labeling (SPL, openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 30, 2026, retrieved October 31, 2026
- Drug recall enforcement reports (openFDA) — U.S. Food and Drug Administration (FDA), FDA data exported October 27, 2026, retrieved October 31, 2026
- NADAC (National Average Drug Acquisition Cost) 2026 — Centers for Medicare & Medicaid Services (CMS), data.medicaid.gov, list of November 4, 2026, retrieved November 7, 2026
Which names get a brand page: a name the NDC Directory lists for a medicine, held by one company (the FDA application holder, or the company named on most of its products), that is not just a description, and that is not the only product of its medicine.